PUZZLE: ALCOHOLISM
The following is a crossword. The answers to the clues all relate to alcohol abuse and its many consequences.

Across
2. This irreversible syndrome caused by thiamine deficiency describes the inability to acquire new memories and often results as a progression from 4 Down (10)
5. A four-part questionnaire in which two or more 'yes' answers have a high correlation for alcoholism, and will identify 8090% of people who are alcohol dependant (abbreviation, 4)
8. This common pub drink can be as strong as 9% (4)
11. Type of anaemia found in alcoholics; the result of marrow suppression/alcohol-related folate deficiency (10)
13. Self-help group that may help alcoholics to remain dry (the 4th emergency service?) (abbreviation, 2)
14. Delirium _ _ _: Slang for acute alcoholic withdrawal, eg, hallucinations, tremor, fits, tachycardia (7)
17. An attack of gout may produce a joint that is red, tender and _ _ _ to touch (3)
18. Often the central issue in alcohol (not a river in Africa) (6)
20. Alcoholic liver disease can mean oestrogens are not metabolised, causing these in men (7)
21. If this organ becomes cirrhotic, 5-year survival is ~50% if drinking continues (5)
22. Physician who gave his name to contracture of the palmar fascia often associated with alcohol (8)
Down
1. Chronic drinking causes these in the gut (6)
3. Arrhythmia often caused by alcohol (abbreviation, 2)
4. Nystagmus, ophthalmoplegia and ataxia: caused by thiamine deficiency, treated with pabrinex.
An encephalopathy named after who? (8)
6. Non-sensitive membrane-bound enzyme whose
levels rise after boozing and return to normal
within 1month of abstinence (5-2)
7. Alcohol can cause this term memory loss (5)
9. Cardiovascularly, C2H5OH can cause people to become _ _ _ (12)
10. The base of an alcoholic gait (4)
12. Irreversible liver damage (9)
15. (Met Bler anagram) Tremor in acute alcohol withdrawal (7)
16. Gland on the face that is often swollen in those who drink to excess (7)
19. Remember, the more you drink the worse it gets... I think (6)

Taken from the forthcoming Puzzling Out… series by Remedica Publishing. For more information or to claim your studentBMJ discount call Rachel on: 020 7554 0741 or contact books@remedica.com
For the answers to the quiz, click on the following link
studentBMJ 2004;12:393-436 November ISSN 0966-6494